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Ultra Pure Peptides - Research Use Only - Raw Material Sourced from the USA

BPC-157 + TB-500
BPC-157 + TB-500 - Image 2
BPC-157 + TB-500 - Image 3

BPC-157 + TB-500

$115.00

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BPC-157 + TB-500

Islip

Pickup available, usually ready in 24 hours

3 Grant Ave.
Ste. B
Islip NY 11751
United States
+16316770030

BPC-157 and TB-500 are two peptides widely researched in regenerative medicine and sports rehabilitation. BPC-157 is a synthetic pentadecapeptide derived from a protein found in gastric juice, while TB-500 is a synthetic version of Thymosin Beta-4. Each peptide promotes healing through distinct mechanisms, with BPC-157 enhancing angiogenesis and reducing inflammation, and TB-500 facilitating cellular migration and tissue repair. Used together, they may offer a synergistic effect in supporting tissue regeneration, soft tissue recovery, and inflammation control.

Applications
  • Musculoskeletal injuries (tendon, ligament, and muscle damage)
  • Post-surgical wound healing and scar reduction
  • Chronic inflammatory conditions (e.g., arthritis, Crohn’s disease, fibromyalgia)
  • Neuroprotection (e.g., traumatic brain injury, neurodegeneration)
  • Cardiac repair (e.g., recovery after myocardial infarction)
Mechanism of Action

BPC-157 – Angiogenesis and Inflammation Control: Promotes VEGF expression for blood vessel growth and downregulates pro-inflammatory cytokines.
BPC-157 – Growth Factor Stimulation: Activates fibroblasts and upregulates TGF-β for tissue repair.
BPC-157 – Gut-Brain Axis Support: May aid gastrointestinal and neurological health.
TB-500 – Cell Migration and Differentiation: Increases actin polymerization, enhancing cell movement to injury sites.
TB-500 – Anti-Fibrotic Effects: Reduces scar tissue by modulating CTGF activity.
TB-500 – Inflammation Modulation: Balances immune responses to support efficient healing

Key Research Studies

BPC-157:

Sikiric et al., 2018:

  • Study focus: Healing and gastrointestinal tract lesions
  • Key findings: BPC-157 supports angiogenesis and reduces inflammation
  • Journal: Current Pharmaceutical DesignDOI: 10.2174/1381612823666170717165151

Sikiric et al., 2020:

  • Study focus: Effects beyond gastrointestinal healing
  • Key findings: Shows benefits in cardiovascular and neurological repair
  • Journal: World Journal of GastroenterologyDOI: 10.3748/wjg.v26.i10.1082

Petrovic et al., 2017:

  • Study focus: Tendon and ligament healing
  • Key findings: Promotes tendon-to-bone healing and musculoskeletal recovery
  • Journal: Journal of Applied Physiology

TB-500 (Thymosin Beta-4):

Goldstein et al., 2012:

  • Study focus: Tissue repair and wound healing
  • Key findings: Enhances cell migration, modulates inflammation
  • Journal: Annals of the New York Academy of SciencesDOI: 10.1111/j.1749-6632.2012.06498.x

Badamchian et al., 2009:

  • Study focus: Angiogenesis and tissue regeneration
  • Key findings: Supports immune modulation and blood vessel growth
  • Journal: Molecular and Cellular BiochemistryDOI: 10.1007/s11010-009-0035-2

Philp et al., 2007:

  • Study focus: Dermal wound healing
  • Key findings: Accelerates wound closure and reduces fibrosis
  • Journal: The Journal of Investigative DermatologyDOI: 10.1038/sj.jid.5701082

Combined Use:

  • Study focus: Combined effects on tendon/ligament healing
  • Key findings: Anecdotal and equine studies suggest faster and more complete recovery
  • Note: No direct human studies yet; suggested mechanisms are complementaryFor more research updates, you may search:

PubMed (https://pubmed.ncbi.nlm.nih.gov/)
Google Scholar (https://scholar.google.com/)
ClinicalTrials.gov (https://clinicaltrials.gov/)

Biological Effects and Benefits

Tissue Regeneration:

Both peptides promote faster recovery of soft tissues, especially muscles, tendons, and ligaments.

Angiogenesis:

BPC-157 enhances blood vessel formation via VEGF expression; TB-500 plays a minor role.

Anti-Inflammatory Action:

Both regulate inflammatory pathways to accelerate healing.

Biological Effects Image

Reduced Scar Tissue Formation:

TB-500 modulates connective tissue to limit fibrosis.

Neuroprotection and Gut-Brain Support:

BPC-157 may aid the nervous system and gut-brain axis.

Cardiovascular Recovery:

TB-500 may support heart tissue repair post-injury.

Molecular Structure

Molecular Structure
  • BPC-157: Pentadecapeptide derived from a gastric protein
  • TB-500: Synthetic peptide derived from Thymosin Beta-4
    Specific sequences not listed in the document, but common literature identifies BPC-157’s sequence as Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val.

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