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Melanotan 2
Melanotan 2 - Image 2

Melanotan 2

$72.00

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Melanotan 2

Islip

Pickup available, usually ready in 24 hours

3 Grant Ave.
Ste. B
Islip NY 11751
United States
+16316770030

Melanotan 2 is a synthetic melanocortin peptide known for stimulating melanin production in the skin, leading to enhanced tanning with minimal sun exposure. It also exhibits secondary effects such as increased libido, appetite suppression, and fat metabolism. Due to its interaction with multiple melanocortin receptors, MT2 has therapeutic potential for erectile dysfunction, skin protection, and metabolic regulation.

Applications
  • Skin tanning and melanin production
  • Erectile dysfunction and libido enhancement
  • Appetite suppression and metabolic support
  • UV protection and reduced sunburn risk
  • Potential anti-inflammatory and insulin-sensitizing effects
Mechanism of Action

Melanocortin Receptor Activation: Binds to MC1R (for pigmentation) and MC4R/MC3R (for libido, appetite, metabolism)
Melanin Production via MC1R: Activates the cAMP pathway → increases tyrosinase activity → stimulates eumelanin (dark pigment) production
Libido and Erectile Function: MC4R stimulation in the hypothalamus leads to dopamine release and increased sexual arousal
Appetite Regulation: MC4R interaction in the hypothalamus reduces hunger signals and may enhance metabolic rate
UV Protection: Elevated melanin acts as a natural sunscreen, limiting UV damage

Key Research Studies

1. Skin Pigmentation and UV Protection

  • Study focus: MT2's impact on tanning and UV resistance
  • Key findings: Enhanced melanin production and long-lasting pigmentation with minimal sun exposure; reduced sunburn risk
  • Reference: Annals of the New York Academy of Sciences, 2006

2. Erectile Dysfunction & Libido Enhancement

  • Study focus: Effectiveness in men with ED
  • Key findings: Improved erectile function and sexual arousal through MC4R stimulation
  • Reference: International Journal of Impotence Research, 2000

3. Appetite Suppression and Fat Loss

  • Study focus: Appetite and weight regulation in animal models
  • Key findings: Reduced food intake and slight fat loss; mediated via hypothalamic MC4R
  • Reference: Endocrinology, 2004

4. Anti-Inflammatory and Metabolic Benefits

  • Study focus: Broader metabolic and inflammatory roles
  • Key findings: Potential improvement in insulin sensitivity and reduction of obesity-related inflammation
  • Reference: Nature Communications, 2019

Biological Effects and Benefits

Skin Tanning:

Stimulates melanin synthesis, enabling darker skin with less UV exposure

Erectile Function Support:

Enhances libido and induces erections by stimulating MC4R/MC3R in the brain

Appetite Suppression:

Reduces food cravings via hypothalamic control, supporting fat loss

Biological Effects Image

UV Protection:

Higher melanin levels reduce DNA damage and risk of sunburn

Fat Metabolism:

May increase energy expenditure and reduce adiposity over time

Anti-Inflammatory Effects:

Potential modulation of inflammation and metabolic pathways

Molecular Structure

Molecular Structure
  • Sequence: Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-NHâ‚‚
  • Molecular Formula: C50H69N15O9
  • Molecular Weight: 1024.18 g/mol
  • Structure Notes: Cyclic peptide that mimics the effects of endogenous melanocyte-stimulating hormones (MSH)

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