TB-500
$164.00
TB-500
Islip
Pickup available, usually ready in 24 hours
3 Grant Ave.
Ste. B
Islip NY 11751
United States
+16316770030
TB-500 is a synthetic peptide modeled after Thymosin Beta-4 (Tβ4), a naturally occurring peptide involved in cellular healing and regeneration. TB-500 is designed to promote recovery, reduce inflammation, and support tissue regeneration across muscle, tendon, ligament, and skin systems. It is especially popular in sports medicine and regenerative therapy for its ability to enhance cell migration and angiogenesis.
Applications
- Muscle injury recovery and repair
- Tendon and ligament healing (e.g., tendinitis, strain, post-surgical rehab)
- Wound healing and post-surgery recovery
- Inflammation reduction (acute or chronic conditions)
- Hair regrowth (e.g., in alopecia)
- Regenerative support in athletic performance and training
Mechanism of Action
Actin Regulation: TB-500 regulates actin polymerization, enabling improved cellular movement and structural repair
Angiogenesis Promotion: Stimulates formation of new capillaries to increase blood flow in injured areas
Fibroblast Activation: Enhances recruitment of fibroblasts to injury sites for ECM remodeling and healing
Inflammation Reduction: Suppresses excess inflammation, allowing for faster and less painful recovery
Tissue Regeneration Support: Boosts cellular proliferation and tissue remodeling in muscle, skin, and connective tissues
Key Research Studies
1. Tissue Regeneration & Angiogenesis
- PMID: https://pubmed.ncbi.nlm.nih.gov/21883065/
- Focus: Cell migration, angiogenesis, and wound healing
- Findings: TB-500 enhances blood vessel formation and fibroblast activation
2. Wound Healing in Mouse Models
- PMID: https://pubmed.ncbi.nlm.nih.gov/16648552/
- Focus: Effects of TB-500 on cutaneous wound closure
- Findings: Accelerated wound healing via increased angiogenesis and tissue regeneration
3. Muscle Regeneration
- PMID: https://pubmed.ncbi.nlm.nih.gov/24097394/
- Focus: Repair of injured muscle tissue
- Findings: Promoted actin polymerization and muscle cell migration
4. Tendon Healing
- PMID: https://pubmed.ncbi.nlm.nih.gov/23239360/
- Focus: TB-500’s role in collagen production and tendon recovery
- Findings: Enhanced tendon regeneration and reduced recovery time in injuries
5. Human Application for Chronic Wounds
- PMID: https://pubmed.ncbi.nlm.nih.gov/20221173/
- Focus: TB-500 use in post-surgical and chronic wound healing in humans
- Findings: Demonstrated acceleration of healing and tissue repair in clinical settings
Biological Effects and Benefits
Accelerated Muscle Recovery:
Promotes repair of muscle fibers after injury or strain
Tendon & Ligament Support:
Stimulates collagen synthesis and tissue remodeling
Enhanced Wound Healing:
Useful in post-surgical recovery and chronic wound treatment
Anti-inflammatory Properties:
Lowers inflammatory cytokines and local swelling
Hair Growth Potential:
Stimulates follicular regeneration in hair loss cases
Angiogenesis:
Improves oxygen and nutrient delivery to injured tissues
Molecular Structure
- Peptide Sequence: Ac-SDKP (Acetyl-Ser-Asp-Lys-Pro)
- Molecular Weight: ~5 kDa
- Type: Synthetic peptide (modified Thymosin Beta-4 fragment)
- Structure Notes: Engineered to enhance tissue healing and biological activity over native Tβ4
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